| Overall | Total | Starts | Used Substitute | Unused Substitute | Scorers |
| Neves R | 164 | Newton S | 20 | Maierhofer S | 1 |
| Coady C | 151 | Silva F | 20 | Mujangi Bia G | 1 |
| Moutinho J | 151 | Collins N | 19 | Murray M | 1 |
| Semedo N | 126 | Kightly M | 18 | Vallejo | 1 |
| Jimenez R | 121 | Miller K | 17 | Ashley-Seal B | 0 |
| Kilman M | 121 | Costa D | 16 | Barnett T | 0 |
| Patricio R | 112 | Costa H | 16 | Batth D | 0 |
| Sa J | 108 | Jones PS | 16 | Bent M | 0 |
| Saiss R | 101 | Trincoa | 16 | Bonatini L | 0 |
| Dendoncker L | 100 | Vinagre R | 14 | Buur O | 0 |
| Jonny | 96 | Cort C | 13 | Campana L | 0 |
| Jarvis M | 95 | Guedioura A | 13 | Campbell C | 0 |
| Berra C | 92 | Gibbs-White M | 12 | Clingan S | 0 |
| Henry K | 92 | Halford G | 12 | Cooper K | 0 |
| Boly W | 89 | Jose W | 12 | Corbeau T | 0 |
| Traore A | 85 | Doyle T | 11 | Ebanks-Landell E | 0 |
| Doyle K | 84 | Iversen S | 11 | Enobakhare B | 0 |
| Ward S | 83 | Traore B | 11 | Giles R | 0 |
| Craddock J | 79 | Bellegarde J | 10 | Gonzalez E | 0 |
| Doherty M | 76 | Blake N | 10 | Gorman J | 0 |
| Neto P | 75 | Hammill A | 10 | Griffiths H | 0 |
| Ait-Nouri R | 74 | Bassong S | 9 | Griffiths L | 0 |
| Hennessey W | 71 | Bueno S | 9 | Hause K | 0 |
| Stearman R | 67 | Hoever K | 9 | Hesketh O | 0 |
| Foley K | 64 | Guedes G | 8 | Holman F | 0 |
| Podence D | 60 | Keogh A | 8 | Hubner J | 0 |
| Hwang H | 57 | Castillo S | 7 | Ikeme C | 0 |
| Jota D | 56 | Okoronkwo I | 7 | Ingimarsson I | 0 |
| Edwards D | 52 | Cavaleiro I | 6 | John C | 0 |
| Lemina M | 51 | Clyde M | 6 | Jordoa B | 0 |
| Zubar R | 51 | Davis D | 6 | Kashloul H | 0 |
| Toti | 45 | Ganea I | 6 | King T | 0 |
| Elokobi G | 43 | Bentley D | 5 | Lembikisa D | 0 |
| Dawson C | 42 | Frimpong E | 5 | Lemina N | 0 |
| Bennett R | 41 | Gudjonsson J | 5 | Lonwijk N | 0 |
| Cunha M | 41 | Vitinha | 5 | Lowe K | 0 |
| Fletcher S | 41 | de Vries D | 4 | Marques C | 0 |
| Gomes J | 39 | Luzhny O | 4 | Marshall A | 0 |
| Hahnemann M | 39 | van Damme J | 4 | Mosquera Y | 0 |
| Milijas N | 38 | Cutrone P | 3 | Moulden | 0 |
| Butler P | 37 | Forde A | 3 | Norris W | 0 |
| Naylor L | 37 | Ruddy JTG (John) | 3 | Ojinnaka T | 0 |
| Mancienne M | 35 | Surman A | 3 | Okoduwa T | 0 |
| Ince P | 32 | Chiwome L | 2 | Perry T | 0 |
| Nunes M | 32 | Cundle L | 2 | Price J | 0 |
| O’Hara J | 32 | Hill M | 2 | Richards L | 0 |
| Ebanks-Blake S | 31 | Iwelumo C | 2 | Ronan C | 0 |
| Hunt S | 30 | Jonsson E | 2 | Rooney N | 0 |
| Irwin D | 30 | Kalajdzic S | 2 | Sanderson D | 0 |
| Camara H | 29 | Mouyokolo S | 2 | Sarkic M | 0 |
| Sarabia P | 29 | Otasowie O | 2 | Shabani M | 0 |
| Kennedy M | 28 | Silas G | 2 | Sonderland A | 0 |
| Jones DF (David) | 27 | Sturridge D | 2 | Spray J | 0 |
| Rae A | 27 | Andrews K | 1 | Storer J | 0 |
| Johnson R | 26 | Chiquinho | 1 | Vokes S | 0 |
| Cameron C | 25 | Chirewa T | 1 | Whittingham M | 0 |
| Marcel | 24 | Fraser N | 1 | Winnall S | 0 |
| Bueno H | 23 | Friend G | 1 | ||
| Oakes M | 21 | Hodge J | 1 |
