| First Team Matches | Second Team Matches | Youth Team Matches | League Debuts | Associated with both clubs | Transfers | Ladies | Programmes |
| Order | Date | Player | Venue | Results | Extra Info | Season | |
| 119 | 21 March 1904 | Smith, E | Molineux | L | 1-6 | 1903/04 | |
| 120 | 21 March 1904 | Pilsbury, C | Molineux | L | 1-6 | 1g | 1903/04 |
| 124 | 14 November 1904 | Hopkins, J | Hyde Road | L | 1-5 | 1g | 1904/05 |
| 134 | 16 September 1905 | James, E | Hyde Road | L | 0-4 | 1905/06 | |
| 135 | 16 September 1905 | Breakwell, A | Hyde Road | L | 0-4 | 1905/06 | |
| 182 | 30 April 1910 | Groves, A | Molineux | W | 3-2 | 1909/10 | |
| 183 | 30 April 1910 | Needham, J | Molineux | W | 3-2 | 1909/10 | |
| 184 | 30 April 1910 | Walker, A | Molineux | W | 3-2 | 1909/10 | |
| 306 | 27 August 1927 | Williams, J | Molineux | D | 2-2 | 1927/28 | |
| 307 | 27 August 1927 | Cock, D | Molineux | D | 2-2 | 1927/28 | |
| 368 | 12 November 1932 | Ellis, J | Maine Road | L | 1-4 | 1932/33 | |
| 386 | 22 December 1934 | Martin, D | Molineux | W | 5-0 | 1934/35 | |
| 409 | 27 February 1937 | Ordish, C | Maine Road | L | 1-4 | 1936/37 | |
| 410 | 27 February 1937 | Westcott, D | Maine Road | L | 1-4 | 1936/37 | |
| 452 | 23 August 1947 | Shorthouse, W | Maine Road | L | 3-4 | 1947/48 | |
| 453 | 23 August 1947 | Brice, G | Maine Road | L | 3-4 | 1947/48 | |
| 454 | 23 August 1947 | Smyth, S | Maine Road | L | 3-4 | 1947/48 | |
| 495 | 18 August 1956 | Hooper, H | Molineux | W | 5-1 | 1g | 1956/57 |
| 498 | 15 December 1956 | Neil, P | Maine Road | W | 3-2 | 1g | 1956/57 |
| 568 | 8 April 1969 | Lutton, R | Molineux | W | 3-1 | 1968/69 | |
| 580 | 24 August 1971 | Sunderland, A | Molineux | W | 2-1 | 1971/72 | |
| 585 | 7 October 1972 | Jefferson, D | Maine Road | D | 1-1 | 1972/73 | |
| 659 | 29 December 1984 | Heywood, D | Maine Road | L | 0-4 | 1984/85 | |
| 660 | 29 December 1984 | Chapman, Cb | Maine Road | L | 0-4 | Sub | 1984/85 |
| 804 | 8 August 1999 | Bazeley, D | Maine Road | W | 1-0 | 1999/00 | |
| 805 | 8 August 1999 | Sinton, A | Maine Road | W | 1-0 | 1999/00 | |
| 854 | 10 April 2004 | Okoronkwo, I | City of Manchester Stadium | D | 3-3 | 2003/04 | |
| 926 | 22 August 2009 | Doyle, K | City of Manchester Stadium | L | 0-1 | Sub | 2009/10 |
| 937 | 30 October 2010 | Mouyokolo, S | Molineux | W | 2-1 | Sub | 2010/11 |
| 948 | 22 April 2012 | de, Vries D | Molineux | L | 0-2 | 2011/12 | |
| 1042 | 21 September 2020 | Silva, F | Molineux | L | 1-3 | Sub | 2020/21 |
| 1060 | 17 September 2022 | Traore, B | Molineux | L | 0-3 | Sub | 2022/23 |
| 1069 | 22 January 2023 | Sarabia, P | Etihad Stadium | L | 0-3 | Sub | 2022/23 |
