Saturday 3 December 1921 at Molineux (Att 14,508)

Wolves (0) 2 (Richards 75, Bissett 80): George, Baugh, Marshall, Rouse, Caddick, Riley, Brooks, Bisset, Edmonds, Hargreaves, Richards.
Port Vale (0) 0: Bourne, R Pursell, P Pursell, Collinge, Connolly, Hampson, Lauder, Page, Tremlow, Agnew, Pearson.

Referee: Mr J Telford (Preston).
Landmark: George Bisset makes his debut following his transfer from Manchester United and scored his first goal.
Position: 19th.