Tuesday 26 December 2000 at Molineux (Att 24,306)

Wolves (0) 0: Oakes, Muscat, Pollet, Lescott, Naylor, Robinson, (Branch 62), Dinning, Andrews (Osborn 69), Sinton (Camara 78), Proudlock, Ndah; Subs Nash, Green.
Preston North End (1) 1 (Andrews 13): Lucas, Alexander (Murdock 48), Jackson, Gregan, Edwards, McKenna, Rankine, Appleton, Anderson (Murphy 51), S Robinson (Cartwright 84), Macken; Subs Moilanen, Ludden.

Referee: Mr B Jordan (Tring).
Booked: Alexander 7, Robinson 37, Muscat 45, Macken 45, Ndah 45, McKenna 57.
History: This was Wolves first League defeat at the hands of Preston since October 1959 and the first at home since November 1952.
Position: 17th.