Saturday 17 October 1925 at Molineux (Att 17,266)

Wolves (1) 4 (Mitton 35, Bowen 47, Phillipson 48 80p): George, Watson, Shaw, Mitton, Charnley, Kay, Harrington, Bowen, Phillipson, Lees, Price.
Southampton (0) 1 (Kay (og)): Yeomans, Parker, Keeping, Shelley, Campbell, Woodhouse, Henderson, Turner, Rawlings, Price, Carr.

Referee: Mr A Grinstead (East Ham).
Order of Goals: W,W,W,s,W.
Penalty: Awarded against Tom Parker for handball.
Position: 5th.