| First Team Matches | Second Team Matches | Youth Matches | League Debuts | Associated with both clubs | Transfers | Ladies | Programmes |
| Order | Date | Player | Venue | Results | Extra Info | Season | |
| 142 | 10 February 1906 | Radford, W | Manor Ground | L | 1-4 | 1905/06 | |
| 366 | 5 November 1932 | Ivill, E | Molineux | L | 1-7 | 1932/33 | |
| 367 | 5 November 1932 | Pincott, F | Molineux | L | 1-7 | 1932/33 | |
| 436 | 31 August 1946 | Williams, B | Molineux | W | 6-1 | 1946/47 | |
| 437 | 31 August 1946 | McLean, A | Molineux | W | 6-1 | 1946/47 | |
| 438 | 31 August 1946 | Wright, W | Molineux | W | 6-1 | 1946/47 | |
| 439 | 31 August 1946 | Hancocks, J | Molineux | W | 6-1 | 1946/47 | |
| 440 | 31 August 1946 | Pye, J | Molineux | W | 6-1 | 3gs | 1946/47 |
| 441 | 31 August 1946 | Ramscar, F | Molineux | W | 6-1 | 1946/47 | |
| 463 | 19 February 1949 | Russell, E | Molineux | L | 1-3 | 1948/49 | |
| 472 | 25 August 1951 | Deeley, N | Molineux | W | 2-1 | 1951/52 | |
| 504 | 7 April 1958 | Jackson, A | Arsenal Stadium | W | 2-0 | 1957/58 | |
| 524 | 14 April 1962 | Goodwin, F | Arsenal Stadium | L | 1-3 | 1961/62 | |
| 534 | 5 September 1964 | Thompson, D | Molineux | L | 0-1 | 1964/65 | |
| 542 | 2 January 1965 | MacLaren, D | Arsenal Stadium | L | 1-4 | 1964/65 | |
| 556 | 23 October 1967 | Williams, E | Molineux | W | 3-2 | 1967/68 | |
| 1054 | 10 February 2022 | Chiquinho | Molineux | L | 0-1 | Sub | 2021/22 |
| 1064 | 12 November 2022 | Lembikisa, D | Molineux | L | 0-2 | Sub | 2022/23 |
| 1080 | 17 August 2024 | Mosquera, Y | Emirates Stadium | L | 0-2 | 2024/25 | |
| 1081 | 17 August 2024 | Gomes, R | Emirates Stadium | L | 0-2 | 2024/25 | |
| 1082 | 17 August 2024 | Larsen, S | Emirates Stadium | L | 0-2 | 2024/25 |
