| A | G | |||||||
| 9 | 26 August 1978 | Elland Road | Leeds United | L | 0-3 | Division 1 | 1 | |
| 10 | 30 August 1978 | Elm Park | Reading | L | 0-1 | League Cup 2 | 1 | |
| 11 | 2 September 1978 | Molineux | Bristol City | W | 2-0 | Division 1 | 1 | |
| 12 | 9 September 1978 | Dell | Southampton | L | 2-3 | Division 1 | 1 | |
| 13 | 11 November 1978 | Molineux | Aston Villa | L | 0-4 | Division 1 | 1 | |
| 14 | 18 November 1978 | Molineux | Leeds United | D | 1-1 | Division 1 | 1 | |
| 15 | 21 November 1978 | Ashton Gate | Bristol City | W | 1-0 | Division 1 | 1 | |
| 16 | 25 November 1978 | White Hart Lane | Tottenham Hotspur | L | 0-1 | Division 1 | 1 | |
| 17 | 9 December 1978 | Burnden Park | Bolton Wanderers | L | 1-3 | Division 1 | 1 | 1 |
| 18 | 16 December 1978 | Molineux | West Bromwich Albion | L | 0-3 | Division 1 | 1 | |
| 19 | 26 December 1978 | Molineux | Birmingham City | W | 2-1 | Division 1 | 1 | |
| 20 | 30 December 1978 | Molineux | Coventry City | D | 1-1 | Division 1 | 1 | |
| 21 | 9 January 1979 | Goldstone Ground | Brighton & Hove Albion | W | 3-2 | FAC 3 | 1 | |
| 22 | 17 January 1979 | Molineux | Southampton | W | 2-0 | Division 1 | 1 | |
| 23 | 20 January 1979 | Portman Road | Ipswich Town | L | 1-3 | Division 1 | 1 | 1 |
| 24 | 27 January 1979 | St James Park | Newcastle United | D | 1-1 | FAC 4 | 1 | |
| 25 | 3 February 1979 | Molineux | Everton | W | 1-0 | Division 1 | 1 | |
| 26 | 10 February 1979 | Loftus Road | Queen`s Park Rangers | D | 3-3 | Division 1 | 1 | |
| 27 | 22 February 1979 | Molineux | Newcastle United | W | 1-0 | FAC 4R | 1 | |
| 28 | 24 February 1979 | Highbury | Arsenal | W | 1-0 | Division 1 | 1 | |
| 29 | 26 February 1979 | Selhurst Park | Crystal Palace | W | 1-0 | FAC 5 | 1 | |
| 30 | 3 March 1979 | Molineux | Middlesbrough | L | 1-3 | Division 1 | 1 | |
| 31 | 7 March 1979 | St James Park | Norwich City | D | 0-0 | Division 1 | 1 | |
| 32 | 10 March 1979 | Molineux | Shrewsbury Town | D | 1-1 | FAC 6 | 1 | |
| 33 | 13 March 1979 | Gay Meadow | Shrewsbury Town | W | 3-1 | FAC 6R | 1 | |
| 34 | 20 March 1979 | Anfield | Liverpool | L | 0-2 | Division 1 | 1 | |
| 35 | 24 March 1979 | Stamford Bridge | Chelsea | W | 2-1 | Division 1 | 1 | |
| 36 | 27 March 1979 | Molineux | Manchester City | D | 1-1 | Division 1 | 1 | |
| 37 | 31 March 1979 | Villa Park | Arsenal | L | 0-2 | FAC SF | 1 | |
| 38 | 3 April 1979 | Molineux | Tottenham Hotspur | W | 3-2 | Division 1 | 1 | |
| 39 | 7 April 1979 | Maine Road | Manchester City | L | 1-3 | Division 1 | 1 | |
| 40 | 10 April 1979 | Molineux | Liverpool | L | 0-1 | Division 1 | 1 | |
| 41 | 14 April 1979 | St Andrews | Birmingham City | D | 1-1 | Division 1 | 1 | |
| 42 | 16 April 1979 | Molineux | Norwich City | W | 1-0 | Division 1 | 1 | |
| 43 | 21 April 1979 | Hawthorns | West Bromwich Albion | D | 1-1 | Division 1 | 1 | |
| 44 | 24 April 1979 | Molineux | Derby County | W | 4-0 | Division 1 | 1 | 1 |
| 45 | 28 April 1979 | Molineux | Bolton Wanderers | D | 1-1 | Division 1 | 1 | |
| 46 | 7 May 1979 | Old Trafford | Manchester Utd | L | 2-3 | Division 1 | 1 |
