| A | G | |||||||
| 47 | 22 August 1979 | Baseball Ground | Derby County | W | 1-0 | Division 1 | 1 | |
| 48 | 25 August 1979 | Molineux | Ipswich Town | W | 3-0 | Division 1 | 1 | |
| 49 | 28 August 1979 | Turf Moore | Burnley | D | 1-1 | League Cup 2/1 | 1 | |
| 50 | 1 September 1979 | Ashton Gate | Bristol City | L | 0-2 | Division 1 | 1 | |
| 51 | 4 September 1979 | Molineux | Burnley | W | 2-0 | League Cup 2/2 | 1 | |
| 52 | 8 September 1979 | Molineux | Crystal Palace | D | 1-1 | Division 1 | 1 | |
| 53 | 15 September 1979 | Goodison Park | Everton | W | 3-2 | Division 1 | 1 | |
| 54 | 22 September 1979 | Molineux | Manchester Utd | W | 3-1 | Division 1 | 1 | |
| 55 | 25 September 1979 | Selhurst Park | Crystal Palace | W | 2-1 | League Cup 3 | 1 | |
| 56 | 29 September 1979 | Highbury | Arsenal | W | 3-2 | Division 1 | 1 | |
| 57 | 6 October 1979 | City Ground | Nottingham Forest | L | 2-3 | Division 1 | 1 | |
| 58 | 9 October 1979 | Molineux | Derby County | D | 0-0 | Division 1 | 1 | |
| 59 | 13 October 1979 | Molineux | Norwich City | W | 1-0 | Division 1 | 1 | |
| 60 | 20 October 1979 | Ayresome Park | Middlesbrough | L | 0-1 | Division 1 | 1 | |
| 61 | 27 October 1979 | Molineux | Aston Villa | D | 1-1 | Division 1 | 1 | |
| 62 | 30 October 1979 | Loftus Road | Queen`s Park Rangers | D | 1-1 | League Cup 4 | 1 | |
| 63 | 3 November 1979 | Anfield | Liverpool | L | 0-3 | Division 1 | 1 | |
| 64 | 6 November 1979 | Molineux | Queen`s Park Rangers | W | 1-0 | League Cup 4R | 1 | |
| 65 | 10 November 1979 | Victoria Ground | Stoke City | W | 1-0 | Division 1 | 1 | |
| 66 | 17 November 1979 | Molineux | Coventry City | L | 0-3 | Division 1 | 1 | |
| 67 | 24 November 1979 | Molineux | West Bromwich Albion | D | 0-0 | Division 1 | 1 | |
| 68 | 1 December 1979 | Maine Road | Manchester City | W | 3-2 | Division 1 | 1 | |
| 69 | 4 December 1979 | Blundell Park | Grimsby Town | D | 0-0 | League Cup 5 | 1 | |
| 70 | 8 December 1979 | Molineux | Bolton Wanderers | W | 3-1 | Division 1 | 1 | |
| 71 | 11 December 1979 | Molineux | Grimsby Town | D | 1-1 | League Cup 5R | 1 | |
| 72 | 15 December 1979 | Elland Road | Leeds United | L | 0-3 | Division 1 | 1 | |
| 73 | 18 December 1979 | Baseball Ground | Grimsby Town | W | 2-0 | League Cup 5RR | 1 | |
| 74 | 21 December 1979 | Molineux | Brighton & Hove Albion | L | 1-3 | Division 1 | 1 | |
| 75 | 26 December 1979 | Molineux | Southampton | D | 0-0 | Division 1 | 1 | |
| 76 | 29 December 1979 | Portman Road | Ipswich Town | L | 0-1 | Division 1 | 1 | |
| 77 | 5 January 1980 | Meadow Lane | Notts County | W | 3-1 | FAC 3 | 1 | 1 |
| 78 | 12 January 1980 | Molineux | Bristol City | W | 3-0 | Division 1 | 1 | |
| 79 | 19 January 1980 | Selhurst Park | Crystal Palace | L | 0-1 | Division 1 | 1 | |
| 80 | 22 January 1980 | County Ground | Swindon Town | L | 1-2 | League Cup SF/1 | 1 | |
| 81 | 26 January 1980 | Molineux | Norwich City | D | 1-1 | FAC 4 | 1 | |
| 82 | 30 January 1980 | Carrow Road | Norwich City | W | 3-2 | FAC 4R | 1 | 1 |
| 83 | 2 February 1980 | Molineux | Everton | D | 0-0 | Division 1 | 1 | |
| 84 | 9 February 1980 | Old Trafford | Manchester Utd | W | 1-0 | Division 1 | 1 | |
| 85 | 12 February 1980 | Molineux | Swindon Town | W | 3-1 | League Cup SF/2 | 1 | |
| 86 | 16 February 1980 | Molineux | Watford | L | 0-3 | FAC 5 | 1 | |
| 87 | 23 February 1980 | Carrow Road | Norwich City | W | 4-0 | Division 1 | 1 | |
| 88 | 26 February 1980 | Molineux | Liverpool | W | 1-0 | Division 1 | 1 | |
| 89 | 1 March 1980 | Molineux | Middlesbrough | L | 0-2 | Division 1 | 1 | |
| 90 | 10 March 1980 | Villa Park | Aston Villa | W | 3-1 | Division 1 | 1 | |
| 91 | 15 March 1980 | Wembley Stadium | Nottingham Forest | W | 1-0 | League Cup F | 1 | |
| 92 | 22 March 1980 | Molineux | Stoke City | W | 3-0 | Division 1 | 1 | |
| 93 | 29 March 1980 | Highfield Road | Coventry City | W | 3-1 | Division 1 | 1 | |
| 94 | 5 April 1980 | Molineux | Tottenham Hotspur | L | 1-2 | Division 1 | 1 | |
| 95 | 7 April 1980 | Dell | Southampton | W | 3-0 | Division 1 | 1 | |
| 96 | 8 April 1980 | Goldstone Ground | Brighton & Hove Albion | L | 0-3 | Division 1 | 1 | |
| 97 | 12 April 1980 | Molineux | Manchester City | L | 1-2 | Division 1 | 1 | |
| 98 | 19 April 1980 | Hawthorns | West Bromwich Albion | D | 0-0 | Division 1 | 1 | |
| 99 | 23 April 1980 | White Hart Lane | Tottenham Hotspur | D | 2-2 | Division 1 | 1 | |
| 100 | 26 April 1980 | Molineux | Leeds United | W | 3-1 | Division 1 | 1 | |
| 101 | 12 May 1980 | Molineux | Nottingham Forest | W | 3-1 | Division 1 | 1 | |
| 102 | 16 May 1980 | Molineux | Arsenal | L | 1-2 | Division 1 | 1 |
