| First Team Matches | Second Team Matches | Youth Team Matches | League debuts | Associated with both clubs | Transfers | Ladies | Programmes |
| Order | Date | Player | Venue | Results | Extra Info | Season | |
| 48 | 15 October 1892 | Griffin, A | North Road | L | 1-10 | 1892/93 | |
| 262 | 16 September 1922 | Best, R | Old Trafford | L | 0-1 | 1922/23 | |
| 404 | 29 August 1936 | Waring, T | Old Trafford | D | 1-1 | 1936/37 | |
| 425 | 12 November 1938 | Parker, W | Old Trafford | W | 3-1 | 1938/39 | |
| 428 | 18 March 1939 | Goddard, R | Molineux | W | 3-0 | 1938/39 | |
| 429 | 18 March 1939 | Steen, A | Molineux | W | 3-0 | 1g | 1938/39 |
| 430 | 18 March 1939 | McAloon, G | Molineux | W | 3-0 | 1938/39 | |
| 481 | 4 October 1952 | Slater, W | Molineux | W | 6-2 | 1952/53 | |
| 483 | 6 March 1953 | Clamp, E | Old Trafford | L | 0-1 | 1953/54 | |
| 484 | 2 October 1954 | Russell, P | Molineux | W | 4-2 | 1954/55 | |
| 507 | 4 October 1958 | Durandt, C | Molineux | W | 4-0 | 1958/59 | |
| 510 | 17 October 1959 | Kirkham, J | Molineux | W | 3-2 | 1959/60 | |
| 511 | 5 March 1960 | Mannion, G | Old Trafford | W | 2-0 | 1959/60 | |
| 512 | 5 March 1960 | Stobart, B | Old Trafford | W | 2-0 | 1959/60 | |
| 513 | 24 September 1960 | Farmer, J | Old Trafford | W | 3-1 | 2gs | 1960/61 |
| 515 | 11 February 1961 | Brodie, C | Molineux | W | 2-1 | 1960/61 | |
| 557 | 30 December 1967 | Ross, S | Molineux | L | 2-3 | 1967/68 | |
| 595 | 16 August 1975 | McNab, R | Molineux | L | 0-2 | 1975/76 | |
| 638 | 29 October 1983 | Blair, A | Old Trafford | L | 0-3 | 1983/84 | |
| 1036 | 19 August 2019 | Neto, P | Molineux | D | 1-1 | Sub | 2019/20 |
| 1038 | 1 February 2020 | Podence, D | Old Trafford | D | 0-0 | Sub | 2019/20 |
| 1072 | 13 May 2023 | Bentley, D | Molineux | L | 0-2 | 2022/23 | |
| 1077 | 1 February 2024 | Fraser, N | Molineux | L | 3-4 | Sub | 2023/24 |
